CRISPR gene editing proves safe in a clinical trial - Nature

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Source link: https://www.nature.com/articles/d41586-020-00339-3
Published by: NATURE on 10 Feb 2020
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The CRISPR–Cas9 enzyme complex (blue and grey) edits DNA (purple). Participants in one of the earliest clinical trials of a CRISPR-based therapy experienced no serious side effects. Credit: Ella Maru Studio/Science Photo Library Preliminary results from one of the earliest clinical trials of

CRISPR—Cas9 provide evidence that the technique is safe and feasible to use for treating human diseases.

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Nature 578, 195 (2020)

doi: https://doi.org/10.1038/d41586-020-00339-3

Science (2020)

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What is CRISPR?
CRISPR (clustered regularly interspaced short palindromic repeats) is a family of DNA sequences found in the genomes of prokaryotic organisms such as bacteria and archaea. These sequences are derived from DNA fragments of bacteriophages that had previously infected the prokaryote. They are used to detect and destroy DNA from similar bacteriophages during subsequent infections. CRISPR technology is a simple yet powerful tool for editing genomes. It allows researchers to easily alter DNA sequences and modify gene function. Its many potential applications include correcting genetic defects, treating and preventing the spread of diseases and improving crops.

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CRISPR gene editing proves safe in a clinical trial - Nature

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